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Grafalon 100mg Injection
Prescription Required
Salt Composition : Human Rabbit Anti-t Cell Immunoglobulin
Manufacturer : NEOVII BIOTECH GmbH, GERMANY
Origin of Medicine : Germany
1 Vial(s) Of 5ml
Introduction to Grafalon 100mg Injection
Grafalon 100mg injection contains active components as Human rabbit anti-T cell immunoglobulin. It is a medication used to treat severe graft-versus-host disease (GvHD). In GvHD, the donor's immune cells (T cells) attack the recipient's body cells. The donor's T cells see the recipient's cells as foreign. GvHD can affect any body part, but it most commonly affects the skin, liver, gut, and lungs. If you have had a severe allergic reaction to this medication or other monoclonal antibodies, you should not receive it. Â
If you have severe kidney or liver disease, Grafalon 100mg injection may worsen your condition, so it should be avoided. It can cross the blood-brain barrier and cause problems in the brain, so it should not be taken if you have active CNS disease. It may worsen your condition. It can cross the placenta and harm the fetus. If you are pregnant or breastfeeding, you should not receive it. It is generally safe for older adults and children. Still, talking to your doctor about the risks and benefits before starting Grafalon 100mg injection is important.
Uses of Grafalon 100mg Injection
Grafalon 100mg injection is used in the following:Â
- Graft-versus-host disease (GvHD)
Therapeutic Effects of Grafalon 100mg Injection
Grafalon 100mg injection depletes T cells, which are the cells that attack the body's tissues in GvHD.It does this by binding to the surface of T cells and activating the immune system to destroy them. It can also prevent T cells from developing in the first place.
Interaction of Grafalon 100mg Injection with other drugs
Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Grafalon 100mg injection, reducing effectiveness by causing undesirable side effects.Â
More Information about Grafalon 100mg Injection
- Stored at room temperature from 2-8°C.
- Keep away from moisture, heat, and light.
- It should not be frozen.
- Keep away from children and pets.
How to consume Grafalon 100mg Injection
Grafalon 100mg injection can be given by intravenous (IV) infusion or intramuscular (IM) injection. The IV route is the most common route of administration. The doctor chooses the administration route based on the patient's needs and preferences.
Safety Advices for Grafalon 100mg Injection
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Pregnancy
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Grafalon 100mg injection is unsafe for pregnant women as it can cross the placenta and harm the fetus.
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Breast Feeding
 ÂGrafalon 100mg injection can pass into breast milk and may harm the baby, so it is safe for breastfeeding women.
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Lungs
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Individuals with respiratory conditions should consult a health care provider before taking Grafalon 100mg injection.
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Liver
  Individuals with liver conditions should consult with their healthcare provider before taking Grafalon 100mg injection.
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Alcohol
 ÂAlcohol can increase the risk of side effects from Grafalon 100mg injection, such as low blood counts and infections. It is safe to take alcohol while taking it.
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Driving
  Grafalon 100mg injection can cause side effects, such as fatigue and dizziness. These side effects can affect your ability to drive. It is important to talk to your doctor about whether it is safe for you to drive while takingÂ
Side Effects of Grafalon 100mg Injection
Grafalon 100mg injection causes some side effects like all medications, although not everyone will experience them.Â
Serious
- Allergic reaction
- Low blood counts
- Infection
- Kidney problems
- Liver problems
- Pneumonitis
- Pulmonary edema
- Thrombosis
- Death
Common
- Fever
- Chills
- Nausea
- Vomiting
- Diarrhea
- Headache
- Muscle pain
- Fatigue
- Rash
- Itching
Word of Advice
It is important to talk to your doctor about these risks and benefits before taking Grafalon 100mg injection as it can cause low blood counts, infection, kidney problems, liver problems, pneumonitis, pulmonary edema, thrombosis, and death. It can cause low blood counts, so it is important to have your blood counts monitored regularly. This will help your doctor to identify any problems early on and take steps to correct them. It is important to take precautions against infection as it can weaken your immune system. This includes washing your hands frequently, avoiding people who are sick, and getting vaccinated against common infections. If you experience hives, itching, rash, shortness of breath, swelling of the face, tongue, or throat, and difficulty breathing, seek medical attention immediately.
FAQs
Q 1. How long does Grafalon 100mg injection treatment last?
The length of Grafalon 100mg injection treatment depends on the condition being treated. It can range from a few days to several weeks.
Q 2. What should I do if I experience side effects from Grafalon 100mg injection?
If you experience any side effects from Grafalon 100mg injection , you should tell your doctor immediately.
Q 3. What are the long-term risks of Grafalon 100mg injection?
The long-term risks of Grafalon 100mg injection are not well known. However, some concern is that it may increase the risk of developing autoimmune diseases.
Q 4. How long does Grafalon 100mg injection take to start working?
The time it takes for Grafalon 100mg injection to start working varies depending on the individual. In some cases, it may start working within a few days. In other cases, it may take several weeks.
Fact Box of Grafalon 100mg Injection
Molecule name: Human rabbit anti-T cell immunoglobulin  | Therapeutic class: Immunomodulator |
Pharmacological class:Â Monoclonal antibody | Indications: Graft-versus-host disease (GvHD) |
References
- Athina L. Yoham, Damian Casadesus, [Revised on 27th May 2021] [Accessed on 13th September 2023], https://www.ncbi.nlm.nih.gov/books/NBK557884/
- CSL Behring GmbH, [Revised on Jun 2019] [Accessed on 13th September 2023], https://www.medicines.org.uk/emc/files/pil.6791.pdf
- CSL Behring (NZ) Ltd, [Revised on Jun 2021] [Accessed on 13th September 2023]https://www.medsafe.govt.nz/profs/Datasheet/r/RhDimmunoglobulinVFinj.pdf
- Neovii Biotech GmbH, [Revised on Jun 2019] [Accessed on 13th September 2023], https://www.hpra.ie/img/uploaded/swedocuments/448358b2-4de2-44fb-b89b-bf36f9f87182.pdf
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