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Lenvenib 4mg Capsule
Prescription Required
Salt Composition : Lenvatinib
Manufacturer : SUN PHARMACEUTICAL INDUSTRIES LTD
Origin of Medicine : India
7 Capsule(s) In A Strip
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Introduction to Lenvenib 4mg Capsule
Lenvenib 4mg Capsule is composed of the active ingredient Lenvatinib. It is a tyrosine kinase inhibitor indicated for progressive or advanced thyroid cancer when radioactive iodine therapy is not beneficial. It is also used to treat previously untreated liver cancer patients who are not eligible for surgical treatment. Anaplastic Thyroid Carcinoma (Advanced thyroid cancer) usually occurs in patients above 60 years of age. It is characterized by an enlarged and hard thyroid gland and hoarseness in the voice due to paralysis of the nerve in the voice box. Hepatocellular carcinoma (liver cancer) develops due to preexisting liver conditions such as cirrhosis or chronic hepatitis B infection. Patients who have had an allergic reaction to Lenvenib 4mg Capsule or any of its components should not take this medication. Patients should inform their dentist or oral surgeon that they are taking Lenvenib 4mg Capsule, as it can impair wound healing and increase the risk of bleeding.
Uses of Lenvenib 4mg Capsule
Lenvenib 4mg Capsule is indicated to treat the following conditions:
- Certain types of advanced thyroid cancer
- Advanced Liver cancer
- Certain types of kidney cancer
- Endometrial cancer
Therapeutic Effects of Lenvenib 4mg Capsule
Lenvenib 4mg Capsule blocks the enzyme receptor tyrosine kinases (RTKs). RTKs develop new blood vessels that supply oxygen and nutrients to the cells and help them grow. This medicine inhibits the receptors that facilitate the growth of blood vessels in tumor cells. RTKs are present in high concentrations in cancer cells, and administration of this medicine slows down the rate of cancer cells’ growth and multiplication.
Interaction of Lenvenib 4mg Capsule with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Lenvenib 4mg Capsule and reduce effectiveness by causing undesirable side effects.
More Information about Lenvenib 4mg Capsule
- Lenvenib 4mg Capsule should be stored at room temperature, between 20°C to 25°C (68°F to 77°F).
- Protected from light.
- Keep it in its original packaging until it is ready to be used.
- Keep reach out of the reach of children and pets.
- Should be disposed of properly.
How to consume Lenvenib 4mg Capsule
Lenvenib 4mg Capsule is an oral medication that is usually taken once a day, at approximately the same time each day, with or without food. It should be taken as prescribed by a doctor or other healthcare provider. These capsules should be swallowed whole with a glass of water. They should not be crushed, chewed, or opened, as this can affect the way the medication is absorbed and decrease its effectiveness. You should not take a double dose to make up for the second dose.
Safety Advices for Lenvenib 4mg Capsule
Pregnancy
Lenvenib 4mg Capsule is unsafe during pregnancy as it can cause fetal harm. It is recommended to avoid this medication during pregnancy.
Breast Feeding
Breastfeeding is not recommended while taking Lenvenib 4mg Capsule, as it can potentially harm the nursing infant.
Lungs
Lenvenib 4mg Capsule can cause side effects that affect the lungs, such as cough, shortness of breath, and difficulty breathing. If a person experiences any of these symptoms while taking it, they should notify their healthcare provider right away.
Liver
Lenvenib 4mg Capsule is primarily metabolized in the liver, so inform your healthcare provider if you have any liver problems or diseases. This medication may also increase liver enzymes, which can be a sign of liver damage or inflammation. Patients taking this medication require regular blood tests to monitor liver function monitored.
Alcohol
It is recommended to avoid consuming alcohol while taking Lenvenib 4mg Capsule, as alcohol can increase the risk of certain side effects associated with the medication, such as stomach ulcers or gastrointestinal bleeding.
Driving
Patients receiving Lenvenib 4mg Capsule should be advised to avoid driving or operating machinery if they experience side effects such as fatigue, dizziness, or blurred vision, impairing a patient's ability to drive or operate machinery safely.
Side Effects of Lenvenib 4mg Capsule
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious:
- Feeling numb or weak on 1 side of the body
- Severe headache
- Fever
- Confusion
- Difficulty speaking
- Vision changes
- Dizziness
- Chest pain or pressure
- Pain in arms, jaw, neck, and back
- Breathing problems
- Severe stomach pain
- Blood clot formation
- Blood in stools or coughing blood
- Liver problems
- Pain or soreness in the mouth, teeth, or jaw
Common:
- High or low BP
- Loss of appetite
- Nausea, vomiting, constipation, diarrhea, or indigestion
- Tiredness
- Hoarse voice
- Leg swelling
- Rashes
- Pain in joints or muscles
- Hair loss
- Sleeplessness
- Protein in urine, frequent urination
- Low potassium, magnesium, and calcium levels in the blood
- Dehydration
- Skin problems
- Gall bladder inflammation
- Increase in the values of cholesterol, thyroid-stimulating hormone, digestive enzymes
- Delayed wound healing
Word of Advice
If you are receiving this medication keep close communication with your healthcare provider and report any concerns or side effects as soon as possible. Avoid getting pregnant and breastfeeding during treatment. Patients should use effective contraception while taking Lenvenib 4mg Capsule and for at least two weeks after stopping treatment. Patients should avoid eating grapefruits as they affect the absorption of this. These capsules should not be given to children
You should use sunscreen and wear protective clothing while outdoors to reduce the risk of sunburn or skin damage. Avoid strenuous activities or exercise until you know how this medication is affecting you. Maintain a healthy and balanced diet during treatment to support your overall health and well-being. By being informed and engaged in your treatment, you can help ensure the best possible outcomes and manage any potential risks or complications associated.
FAQs
Q 1. Can Lenvenib 4mg Capsule cause infertility?
Lenvenib 4mg Capsule can cause changes in menstrual periods and may affect fertility in some women. Patients should discuss their fertility concerns with their healthcare provider before starting this medication.
Q 2. Can Lenvenib 4mg Capsule cause hair loss?
Yes, hair loss is a potential side effect of Lenvenib 4mg Capsule. However, not all patients experience hair loss while taking this medication. Patients should discuss the potential side effects with their healthcare provider before starting treatment.
Q 3. Can Lenvenib 4mg Capsule cause heart problems?
Lenvenib 4mg Capsule can cause high blood pressure, which may increase the risk of heart problems. Patients should have their blood pressure monitored regularly while taking this medication.
Q 4. Can I go for teeth extraction if I am taking Lenvenib 4mg Capsule?
Before undergoing any dental procedures, it's important to inform your dentist and healthcare provider that you are taking Lenvenib 4mg Capsules. It can increase the risk of bleeding, and dental procedures that involve cutting or removing tissue may increase this risk further. Your healthcare provider and dentist may recommend taking certain precautions, such as temporarily stopping of this medication before the procedure or adjusting your medication dose.
Q 5. Can Lenvenib 4mg Capsule cause vision problems?
Yes, vision problems are a potential side effect of Lenvenib 4mg Capsule. Patients should report any changes in vision to their healthcare provider immediately.
Q 6. Can Lenvenib 4mg Capsule be used in children?
Lenvenib 4mg Capsule is not currently approved for use in children. The safety and efficacy in children have not been established.
Fact Box of Lenvenib 4mg Capsule
Molecule name: Lenvatinib | Therapeutic class: Anticancer |
Pharmacological class: Tyrosine kinase inhibitor | Indications: 1. Certain types of advanced thyroid cancer 2. Advanced liver cancer 3. Endometrial cancer 4. Certain kidney cancer |
References
- Eisai Europe Limited, Electronic Medicines Compendium (EMC), [Revised on Mar 2021] [Accessed on 20th April 2023], https://www.medicines.org.uk/emc/files/pil.6840.pdf
- Suyama and Iwase, Lenvatinib: A promising molecular targeted agent for multiple cancers, Cancer Control, 2018, 25, 1-5, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056795/pdf/4/1177 473274818789361.pdf
- Q.M. Anstee, D.E.J. Jones, Liver and Biliary Tract Disease, Davidson’s Principles and Practice of Medicine, 22nd Edition, 2014, 921-988.
- M.W.J. Strachan, J. Newell-Price, Endocrine disease, Davidson’s Principles & Practice of Medicine, 22nd Edition, 2014, 733-796.
- Eisai Inc U.S Food and Safety Drug Administration (FDA) [Last revised Aug 2018], [Accessed on 20th April 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/206947s007lbl.pdf
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