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Tazowin Injection
Prescription Required
Salt Composition : Pentazocine Lactate
Manufacturer : THEMIS MEDICARE
Origin of Medicine : India
1 Vial(s) Of 1ml
Introduction to Tazowin Injection
Tajowin injection contains an active component such as Pentazocine lactate. It is a medication used for pain management. After surgical procedures, patients often experience pain as part of the recovery process. It can help manage the pain during this period. It might be used to alleviate pain caused by injuries, such as fractures, sprains, or soft tissue damage. It can be used as part of a pain management plan for cancer patients. It may be considered for chronic pain conditions like severe back pain, neuropathic pain, and other conditions where non-opioid medications have proven ineffective. This medication may sometimes be used during labor to help manage the pain associated with contractions. It can also be administered to reduce pain and anxiety associated with certain medical procedures, such as wound care or dressing changes.
Individuals who have a known hypersensitivity or allergy to Tajowin injection or any of its components should not use this medication. It should be avoided in individuals with severe respiratory conditions or compromised respiratory function. It should be avoided in individuals with conditions that can be worsened by CNS depression, such as head injuries or increased intracranial pressure. It should not be used in combination with MAOIs or within 14 days of discontinuing MAOIs due to the risk of hypertensive crisis. Elderly patients may be more susceptible to this medication's CNS depressant effects and other side effects, so its use should be carefully considered. Tajowin injection is an opioid analgesic, and its use in children should be approached with caution and under the guidance of a pediatrician or a healthcare providerÂ
Uses of Tazowin Injection
Tajowin injection is used in the following:
- Postoperative pain
- Injury and trauma pain
- Cancer pain
- Chronic pain
- Labor pain
- Painful medical procedures
- Emergency pain relief
- Pain from medical conditions
- Preoperative sedation
- Diagnostic procedures
Therapeutic Effects of Tazowin Injection
Tajowin injection involves binding to both kappa opioid receptors as an agonist and mu-opioid receptors as a weak antagonist. This dual activity modulates pain perception and transmission in the central nervous system, relieving pain. Its partial agonist activity at mu receptors relieves pain while limiting the potential for respiratory depression, though it still carries risks of side effects and misuse.
Interaction of Tazowin Injection with other drugs
Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Tajowin injection, reducing effectiveness by causing undesirable side effects.Â
More Information about Tazowin Injection
- Store at room temperature, between 15°C and 30°C
- Keep away from moisture, heat, and light.
- It should not be frozen.
- Keep away from children and pets.
How to consume Tazowin Injection
The common routes of administration of Tajowin injection include intramuscular (IM) injection and intravenous (IV) injection. Depending on the situation and the healthcare provider's recommendations, it can be administered through various routes.Â
Safety Advices for Tazowin Injection
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Pregnancy
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Tajowin injection should be used cautiously during pregnancy. It's important to consult your healthcare provider before using this medication while pregnant.Â
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Breast Feeding
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Tajowin injection passes into breast milk and can affect nursing infants. It's not safe to use this medication while breastfeeding
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Lungs
  Tajowin injection can depress the respiratory system, potentially causing breathing difficulties, especially in individuals with lung conditions. Inform your healthcare provider about any lung issues you have before taking pentazocine.
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Liver
  Tajowin injection metabolism may involve the liver, and individuals with severe liver impairment should consult their healthcare provider before using this medication.
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Alcohol
 ÂAlcohol can enhance the central nervous system depressant effects of Tajowin injection , leading to increased drowsiness and respiratory depression, so it is not safe to take this medication with alcohol.
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Driving
  It is not safe to take Tajowin injection as it can cause drowsiness, dizziness, and impaired coordination.
Side Effects of Tazowin Injection
Tajowin injection causes some side effects like all medications, although not everyone will experience them.Â
Serious
- Respiratory depression
- Dependence and addiction
- Hypotension
- Central nervous system effects
- Gastrointestinal effects
- Allergic reactions
- Withdrawal
Common
- Drowsiness and dizziness
- Nausea and vomiting
- Sweating
- Constipation
- Dry mouth
- Headache
- Lightheadedness
- Weakness or fatigue
- Mood changes
- Urinary retention
Word of Advice
Inform your healthcare provider of your medical history, allergies, and current medications, as certain conditions or medications can interact with Tajowin injection. If you have respiratory issues, consult your healthcare provider due to the risk of respiratory depression. Consider your liver and kidney function, as adjustments to the dosage might be necessary. Those with a history of substance abuse should exercise caution, as it carries the potential for dependence and misuse. Its dosages should be closely monitored and adjusted by your healthcare provider. It is advisable not to stop the medication abruptly, and any changes in mood or mental health should be communicated. Be cautious about accidental overdose and avoid sharing medication. In case of emergencies, know the signs of allergic reactions. Maintain open communication with your healthcare provider, attend follow-up appointments, and educate yourself about the medication for informed decision-making. Always follow your healthcare provider's instructions for this medication's safe and appropriate use.
FAQs
Q 1. What should I do if I miss a dose of Tajowin injection?
If you miss a dose, take it as soon as you remember. However, if it's close to the next dose, skip it and continue with your regular dosing schedule.
Q 2. Can Tajowin injection be addictive?
Yes, pentazocine has the potential to be habit-forming. To minimize the risk of dependence, take it only as your doctor prescribes, and don't share it with others.
Q 3. How long can I take Tajowin injection?
Tajowin injection is typically prescribed for short-term pain relief, as its long-term use can increase the risk of side effects, tolerance, and dependence. Your healthcare provider will determine the appropriate duration of treatment based on your condition.
Q 4. Does Tajowin injection affect breathing?
Yes, pentazocine can slow down breathing, especially if used in high doses or for prolonged periods. It's essential to discuss any existing breathing issues or lung conditions with your doctor before using this medication.
Q 5. How does Tajowin injection compare to other pain medications?
Tajowin injection has a unique mechanism of action, acting as a partial agonist and antagonist on certain opioid receptors. It's important to discuss your pain management needs and any previous experiences with pain medications with your doctor to determine the best option for you.
Q 6. Can I adjust the dose of Tajowin injection on my own?
No, it's important not to adjust the dose of Tajowin injection on your own. Any changes to your dosage should be discussed with your healthcare provider to ensure safe and effective pain management.
Fact Box of Tazowin Injection
Molecule name: Pentazocine lactate | Therapeutic class: Opioid receptor agonist-antagonists. |
Pharmacological class: Analgesics | Indications:Â 1. Postoperative pain 2. Injury and trauma pain 3. Cancer pain 4. Chronic pain 5. Labor pain 6. Painful medical procedures 7. Emergency pain relief 8. Pain from medical conditions 9. Preoperative sedation 10. Diagnostic procedures |
References
- Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Opioids, analgesia and pain management, 12th edition, 2011, 509.
- KD Tripathi, Essentials of Medical Pharmacology, Opioid analgesics and antagonists, 7th edition, 2013, 480 - 482.
- Hospira, Inc, US Food and Drug Administration, [Revised on Dec 2016] [ Accessed on 31 August 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/016194s079s080lbl.pdf
- Mylan, Electronic medicines compendium (EMC), [ Revised on 22nd Aug 2021] [ Accessed on August 31st, 2023],https://www.medicines.org.uk/emc/product/8832/smpc#grefÂ
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