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Trilavir L Tablet
Prescription Required
Salt Composition : Efavirenz,lamivudine,tenofovir Disoproxil Fumarate
Manufacturer : LAURUS LABS LTD
Origin of Medicine : India
30 Tablet(s) In A Bottle
Introduction to Trilavir L Tablet
Trilavir L tablet contains the active substance called Efavirenz, Lamivudine, Tenofovir Disoproxil Fumarate. Efavirenz is an antiretroviral family in the class of medications called nonnucleoside reverse transcriptase inhibitors (NNRTIs). Whereas, Lamivudine and Tenofovir Disoproxil Fumarate is an antiretroviral or antiviral medicine belonging to the class of medications called nucleotide reverse transcriptase inhibitors (NRTI).Â
Do not take Trilavir L tablet if you are allergic to Efavirenz, Lamivudine, Tenofovir Disoproxil Fumarate, or its other medical ingredients. Patients diagnosed with pancreatitis or at risk of pancreatitis should take this combination of medicine cautiously. During this treatment, your doctor may periodically monitor your blood counts, bone mineral density, and liver and kidney parameters to prevent serious complications. Report to your doctor if you have or had a history of heart failure (QT prolongation), seizures, mental health issues, pancreatitis (inflammation in the pancreas), bone disease (osteonecrosis - the death of bone tissue), fractures, liver (chronic hepatitis B or C), or kidney problems.Â
Inform your doctor if you are planning to get pregnant or think you may be pregnant. Breastfeeding is not recommended while taking Trilavir L tablet, due to the potential transmission of HIV from the mother to the baby.
Uses of Trilavir L Tablet
- Treatment of HIV infections
Therapeutic Effects of Trilavir L Tablet
The reverse transcriptase enzyme produces copies of the DNA of HIV. Lamivudine and Tenofovir are Nucleoside reverse transcriptase inhibitors. Efavirenz is a Nonnucleoside Reverse Transcriptase Inhibitor that directly inhibits the enzyme reverse transcriptase. This blocks the replication and reproduction of the virus.
Interaction of Trilavir L Tablet with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. Certain medications interact with Trilavir L tablet and reduce its effectiveness by causing undesirable side effects.Â
More Information about Trilavir L Tablet
- Store at 30°C.
- Protect the medicine from light and excessive moisture.
- Keep the medicine out of reach of children and pets.
How to consume Trilavir L Tablet
It is an orally available prescription drug. Your doctor will decide the dose and duration of Trilavir L tablet based on the disease condition and other factors. Always take this medicine as prescribed by your doctor. Take the tablet at the same time. Do not take an additional dose to compensate for the missed dose.
Safety Advices for Trilavir L Tablet
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Pregnancy
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Notify your healthcare professional if you are pregnant or planning to have a baby think you may be pregnant. Your physician will conduct regular tests to monitor the development of your child. Ask for suggestions before taking the Trilavir L tablet.
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Breast Feeding
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It is unsafe to breastfeed if you are with HIV infection. Consult your doctor for more information about Trilavir L tablet.Â
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Lungs
  It is unknown whether Trilavir L tablet is safe for patients with lung problems. Inform your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.
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Liver
  Inform your physician about any underlying liver disorders before taking Trilavir L tablet should be used cautiously in liver disease patients. Your doctor may monitor your liver enzymes. Consult your physician before taking this medicine.
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Alcohol
 ÂDo not consume alcohol while taking the Trilavir L tablet, as this injection may cause drowsiness with alcohol
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Driving
  It is unsafe to drive while taking Trilavir L tablet because this medicine might cause vision problems and tiredness, so avoid driving and operating machinery during this treatment.
Side Effects of Trilavir L Tablet
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious:
- Rapid breathing
- Drowsiness
- Nausea, vomiting, and stomach pain
- Severe allergic reactions
- Severe mood disturbances, depression, and suicidal thoughts
- Confusion, forgetfulness, seizures, and tremor
- Liver toxicity
- Kidney damage
- Autoimmune disorders
Common:
- Bloating, flatulence
- Headache
- Sleeplessness
- Skin reactions
- Wheezing, swelling, or lightheadedness
- Hair loss
- Diarrhea
- Bone disorders
- Weakness
- Anemia
Word of Advice
Inform your doctor about your underlying infections. If you have advanced HIV (AIDS), you may develop signs of infection and inflammation or worsen the signs of an existing infection once treatment is started. Report your doctor for side effects. It is mandatory to tell your medical professional if you are consuming other medicines that may damage your kidneys. Always consume the dose recommended by your doctor. Trilavir L tablet does not reduce the risk of transmitting HIV to others via sexual contact or blood contamination. You must continue the medication to avoid this complication.
FAQs
Q 1. What should you not take with Trilavir L tablet?
It is not recommended to take Trilavir L tablet with other HIV medications. Tell your healthcare provider if you are taking other medications, over-the-counter drugs, vitamins, or herbal supplements.
Q 2. How can Trilavir L Tablets be stored?
Store Trilavir L tablets below 30°C in its original container, away from the reach of children.
Q 3. What should you do if you miss a dose of Trilavir L Tablet?
If you missed a dose ofTrilavir L Tablet, take one tablet as soon as you remember. However, if it is almost time for your next dose, skip this dose and take your next dose as per schedule. Do not take two doses to compensate for the missed dose.
Q 4. What are the required laboratory parameters before taking Trilavir L treatment?
If you are an adolescent or adult of childbearing potential, your healthcare provider will perform a pregnancy test before prescribing this treatment. Other prominent tests include HBV infection, serum creatinine, estimated creatinine clearance, urine glucose, and urine protein
Q 5. How do you know if you are hypersensitive to Trilavir L?
Watch out for symptoms like severe rash, Steven’s Johnsons syndrome, and swelling of the face or lips, and immediately reach out to your healthcare provider if you experience any of these symptoms.
Fact Box of Trilavir L Tablet
Molecule name: Efavirenz, Lamivudine, Tenofovir disoproxil fumarate | Therapeutic class: Antiretroviral |
Pharmacological class:Â 1. Nucleoside reverse transcriptase inhibitors (NRTIs) 2. Nonnucleoside reverse transcriptase inhibitors (NNRTIs) | Indications: Human Immunodeficiency Virus (HIV-1) infection |
References
- Macleods Pharmaceuticals Limited, US Food and Drug Administration, [Revised on Mar 2019] [Accessed on 23rd Apr 2021], https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/210649s000lbl.pdf
- Clinical info HIV.gov, Efavirenz / Lamivudine / Tenofovir Disoproxil Fumarate - Patient | NIH (hiv.gov)
- KD Tripathi, Antiviral Drugs (Anti-retrovirus), Essentials of Medical Pharmacology, 8th Edition, 2019, 860-872.
Disclaimer
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