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Vonavir Tablet
Prescription Required
Salt Composition : Efavirenz,emtricitabine,tenofovir Disoproxil Fumarate
Manufacturer : EMCURE PHARMACEUTICALS LTD
Origin of Medicine : India
30 Tablet(s) In A Bottle
Introduction to Vonavir Tablet
Vonavir Tablets contain two active substances, Emtricitabine and Tenofovir disoproxil fumarate. These medications are a part of the standard combination therapy for HIV, known as antiretroviral therapy (ART). It is a combination drug regimen that is commonly used for the effective treatment of HIV-1 infection. When used correctly and consistently, Vonavir tablets have demonstrated high efficacy in HIV treatment and prevention.Â
Antiviral medications help postpone the effects of AIDS and enhance the overall quality of life. For individuals with high viral loads, this combo therapy is ideal. Although this medication greatly lowers the risk of viral infection, it does not treat HIV, and there are still chances that HIV will spread to other individuals. It is given to adults and kids over the age of 12 with a body weight of more than 35 kg.
These should not be used in individuals with known hypersensitivity or severe allergic reactions to Emtricitabine, Tenofovir disoproxil fumarate, or any medication components. This medication is not recommended in individuals with severe renal impairment or end-stage renal disease who are not receiving hemodialysis.
Uses of Vonavir Tablet
Vonavir Tablet is used to treat HIV-1 infection.
Therapeutic Effects of Vonavir Tablet
Vonavir Tablet has therapeutic effects in treating HIV infection and pre-exposure prophylaxis (PrEP). They work by inhibiting HIV replication, reducing viral load, improving immune function, and slowing the progression of HIV disease. In individuals with HIV, these medications help control the virus, maintain a low viral load, and improve overall health outcomes.
Interaction of Vonavir Tablet with other drugs
Inform your healthcare provider about all your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Vonavir Tablet, reducing effectiveness by causing undesirable side effects.Â
More Information about Vonavir Tablet
- Store at a temperature between 20°C to 25°C (68°F to 77°F).
- Keep away from moisture, heat, and light.
- It should not be frozen.
- Keep it in its original packaging.
- Keep away from children and pets.
How to consume Vonavir Tablet
To properly consume Vonavir Tablet, follow your healthcare provider's instructions regarding dosage, frequency, and duration. Take it with or without food, swallowing the tablets or capsules with water. Adhere to the prescribed dosing schedule; do not alter the dosage without consulting your healthcare provider.
Safety Advices for Vonavir Tablet
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Pregnancy
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If you are pregnant or plan to become pregnant, it is crucial to consult with your healthcare provider before taking Vonavir Tablet.
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Breast Feeding
 ÂVonavir Tablet is excreted into human breast milk, but the potential risks to the infant are not well established. So patients should consult a doctor before taking it.
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Lungs
  Suppose you have a history of lung disease or are experiencing respiratory symptoms while taking it. Then it is important to consult the healthcare provider for a thorough evaluation before taking Vonavir Tablet.
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Liver
  The safety of Vonavir Tablet in individuals with liver disease may depend on the specific type and severity of liver disease and other factors. It is important to consult with a healthcare provider.
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Alcohol
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It is generally recommended to avoid excessive alcohol consumption while taking Vonavir Tablet or any medication. Alcohol can interact with this medication and affect liver function.
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Driving
  Some people experience side effects, including dizziness, drowsiness, or fatigue, while taking Vonavir Tablet. Suppose anyone experiences any of these side effects or any other symptoms that may interfere with your ability to drive safely. In that case, avoid driving or operating heavy machinery.
Side Effects of Vonavir Tablet
Vonavir Tablets cause side effects like all medications, although not everyone will experience them.Â
Serious:
- Kidney problems or renal toxicity
- Decreased bone mineral density or bone loss
- Lactic acidosis (a huge accumulation of lactic acid in the blood)
- Hepatic steatosis (fat accumulation in the liver)
- Immune reconstitution syndrome (a paradoxical worsening of pre-existing infections or inflammatory conditions when the immune system strengthens)
Common:
- Nausea
- Diarrhea
- Headache
- Fatigue
- Dizziness
- Insomnia
- Rash
Word of Advice
If you are considering taking Vonavir Tablet, knowing the potential risks and warnings associated with this medication is important. Pregnancy and breastfeeding require individual evaluation and consultation with a doctor to weigh the benefits against potential risks. It should be used cautiously in individuals with pre-existing conditions such as liver disease, kidney disease, or bone disorders, as it may exacerbate them. Close monitoring and appropriate management are necessary in these cases. Adherence to these precautions and regular monitoring and communication with the healthcare provider can help ensure safe and effective use.
FAQs
Q 1. Can Vonavir Tablet be taken with other antiretroviral medications?
Vonavir Tablet is often combined with other antiretroviral medications as part of a multidrug regimen for treating HIV infection. The specific combination of medications will depend on individual health status, treatment history, and potential drug interactions.
Q 2. Can Vonavir Tablet be safely used by older adults?
Vonavir Tablet can be used in older adults. Still, dosage adjustments or additional monitoring may be necessary, as age-related changes in kidney and liver function can affect medication clearance. It is important to discuss individual health status and any concerns with a healthcare provider.
Q 3. Can Vonavir Tablet be used in individuals with pre-existing bone conditions?
Individuals with pre-existing bone conditions, such as osteoporosis or osteopenia, may require careful monitoring and management when using Vonavir Tablet. It is important to discuss any underlying bone conditions with your healthcare provider to ensure appropriate bone health monitoring and potential supplementation.
Q 4. Can Vonavir Tablet prevent all forms of HIV transmission?
Vonavir Tablet, when used as PrEP, significantly reduces the risk of HIV transmission through sexual activity or injection drug use. However, they do not provide 100% protection against HIV, and it is important to continue practicing safe sex and taking other preventive measures.
Q 5. Can Vonavir Tablet cause lactic acidosis?
Although rare, Vonavir Tablet has been associated with the risk of lactic acidosis. Lactic acidosis is a serious condition characterized by the accumulation of lactic acid in the blood. It is important to promptly report any symptoms such as unusual weakness, rapid breathing, nausea, vomiting, abdominal pain, or unexplained muscle pain to your healthcare provider while taking it.
Q 6. Are any specific tests or monitoring required for bone health while taking Vonavir Tablet?
Monitoring of bone mineral density may be recommended for individuals on long-term treatment with Tenofovir disoproxil fumarate. Your healthcare provider may request bone density scans or blood tests to assess bone health and determine if any interventions or additional treatments are necessary.
Q 7. Can Vonavir Tablet be used in individuals with liver or kidney disease?
Vonavir Tablets should be used cautiously in individuals with liver or kidney impairment. Dose adjustments or alternative treatment options may be necessary.
Fact Box of Vonavir Tablet
Molecule name: Emtricitabine and Tenofovir disoproxil fumarate | Therapeutic class: Antiretroviral agents |
Pharmacological class: Nucleoside reverse transcriptase inhibitors (NRTIs) | Indications: HIV- 1 Infection |
References
- KD Tripathi, Antiviral Drugs (Anti-retrovirus), Essentials of Medical Pharmacology, 8th Edition, 2019, 860-872.
- Tillomed Laboratories Limited, Electronic Medicines Compendium (EMC), [Revised on Apr 2020] [Accessed on 19th May 2023], https://www.medicines.org.uk/emc/files/pil.11636.pdf
- Gilead Sciences, Inc, US Food and Drug Administration, [ Revised on March 2016] [ Accessed on 19th May 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/021752s047lbl.pdf
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