All Substitutes
Loading...
Disclaimer
Did you find this information helpful?
  Â
Xapavir LT Tablet
Prescription Required
Salt Composition : Dolutegravir,lamivudine,tenofovir Disoproxil Fumarate
Manufacturer : NATCO PHARMA LTD
Origin of Medicine : India
30 Tablet(s) In A Bottle
Introduction to Xapavir Lt Tablet
Xapavir LT tablet consists of the active substance called Dolutegravir, Lamivudine, Tenofovir disoproxil fumarate. Dolutegravir is an antiviral medicine belonging to the integrase inhibitor family. Lamivudine, Tenofovir disoproxil fumarate, which belongs to the antiretroviral medicine class. This medicine treats HIV (human immunodeficiency virus) infection in adults and children with 40kg or greater. It is a nucleotide reverse transcriptase inhibitor (NRTI) and works by inhibiting the enzymes (HIV reverse transcriptase), which is important for virus replication. While consuming this medicine, you may still develop infections related to HIV. Although effective antiretroviral therapy reduces the risk, HIV transmission is still possible when using this medication. Contact your doctor for more information.Â
Do not take Xapavir LT tablet if you are allergic to Dolutegravir, Lamivudine, Tenofovir Disoproxil Fumarate, or its other medical ingredients. Patients diagnosed with pancreatitis or at risk of pancreatitis should take this combination of medicine cautiously. During this treatment, your doctor may periodically monitor your blood counts, bone mineral density, liver and kidney parameters to prevent serious complications. Notify your doctor if you have or had a history of lactic acidosis (excess lactic acid), pancreatitis (inflammation in the pancreas), bone disease (osteonecrosis - the death of bone tissue), fractures, liver (chronic hepatitis B), or kidney problems.Â
Inform your doctor if you are planning to get pregnant or think you may be pregnant. Breastfeeding is not recommended while taking Xapavir LT tablet due to the potential transmission of HIV infection to the baby from mother.
Uses of Xapavir Lt Tablet
- Human Immunodeficiency Virus 1 (HIV) infection in adults and children (40kg or greater).
Therapeutic Effects of Xapavir Lt Tablet
Xapavir LT tablet lowers HIV by inhibiting its replication. It increases the number of CD4 (T) cells, enabling the immune system to fight other infections. This lowers the risk of severity and death associated with a weak immune system.
Interaction of Xapavir Lt Tablet with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. Certain medications interact with Efavirenz, Lamivudine, Tenofovir Disoproxil Fumarate and reduce their effectiveness by causing undesirable side effects.Â
More Information about Xapavir Lt Tablet
- Store at 30°C.
- Protect the medicine from light and excessive moisture.
- Keep the drug out of reach of children and pets.
How to consume Xapavir Lt Tablet
It is taken orally. Your doctor will decide the dose and duration of Xapavir LT based on the disease condition and other factors. Always take this medicine as prescribed by your doctor. Take the tablet at the same time. Do not take an additional dose to compensate for the missed dose. Do not chew, dissolve, crush, or break the tablet.Â
Safety Advices for Xapavir Lt Tablet
 Â
Pregnancy
 Â
Notify your healthcare professional if you are pregnant or planning to have a baby think you may be pregnant. Your physician will conduct regular tests to monitor the development of your child. Ask for suggestions before taking the Xapavir LT tablet.
 Â
Breast Feeding
 Â
It is unsafe to breastfeed if you are with HIV infection. Consult your doctor for more information about Xapavir LT tablets.Â
 Â
Lungs
  It is unknown whether Xapavir LT tablet is safe for patients with lung problems. Inform your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.
 Â
Liver
  Inform your physician about any underlying liver disorders before taking Xapavir LT tablet should be used cautiously in liver disease patients. Your doctor may monitor your liver enzymes. Consult your physician before taking this medicine.
 Â
Alcohol
 ÂDo not consume alcohol while taking the Xapavir LT tablet, as this injection may cause drowsiness with alcohol.
 Â
Driving
  It is unsafe to drive while taking Xapavir LT tablet because this medicine might cause vision problems and tiredness, so avoid driving and operating machinery during this treatment.
Side Effects of Xapavir Lt Tablet
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious:
- Rapid breathing
- Drowsiness
- Nausea, vomiting, and stomach pain
- Severe allergic reactions
- Severe mood disturbances, depression, and suicidal thoughts
- Confusion, forgetfulness, seizures, and tremor
- Liver toxicity (yellow skin, dark urine, light-colored skin)
- Kidney damage
Common:
- Bloating, flatulence
- Headache
- Sleeplessness
- Skin reactions
- Wheezing, swelling, or lightheadedness
- Hair loss
- Diarrhea
- Bone disorders
- Weakness
- Anemia
Word of Advice
Inform your doctor about your underlying infections. If you have advanced HIV (AIDS), you may develop signs of infection and inflammation or worsen the signs of an existing infection once treatment is started. Report your doctor for side effects. It is mandatory to tell your medical professional if you are consuming other medicines that may damage your kidneys. Always consume the dose recommended by your doctor. Xapavir LT tablet does not reduce the risk of transmitting HIV to others via sexual contact or blood contamination. You must continue the medication to avoid this complication. Always use effective contraception to have safe sex.Â
FAQs
Q 1. When should you report to your healthcare provider while taking Xapavir LT?
Reach out to your healthcare provider if you experience symptoms of hypersensitivity reactions or lactic acidosis and any other side effects. Also, reach out to your doctor if you have overdosed on the Xapavir LT tablet.
Q 2. Can I compensate for the missed dose of Xapavir LT?
No, you should not try to compensate for the missed medicine. Suppose you forget to take Xapavir LT tablet. Kindly continue the normal schedule. Do not double-dose the medicine to make up for the missed dose
Q 3. Is that okay to refrigerate the Xapavir LT?
Store Dolutegravir, Lamivudine,Tenofovir disoproxil fumarate tablets below 30°C in its original container, away from the reach of children.
Q 4. What are the symptoms of lactic acidosis?
Unusual weakness, tiredness, muscle pain, trouble breathing, stomach pain, nausea, vomiting, dizziness, lightheadedness, irregular heartbeat, and feeling cold, especially in your legs and arms, are the most prominent symptoms of lactic acidosis.
Q 5. How can I manage side effects while taking Xapavir LT tablet?
Contact your doctor instantly if you experience any side effects while taking Xapavir LT tablet. Your physician may also recommend over-the-counter or prescription medications to help manage your side effects.
Fact Box of Xapavir Lt Tablet
Molecule name: Dolutegravir + Lamivudine + Tenofovir disoproxil fumarate | Therapeutic class: Antiretrovirals |
Pharmacological class:Â Â 1. Integrase inhibitor 2. Nucleoside reverse transcriptase inhibitors (NRTIs) | Indications:Â HIV-1 Infection
|
References
- Aurobindo Pharma, US Food and Drug Administration, [Revised on Apr 2018] [Accessed on 22nd May 2023] https://www.accessdata.fda.gov/drugsatfda_docs/pepfar/209618PI.pdf
- KD Tripathi, Antiviral Drugs (Anti-retrovirus), Essentials of Medical Pharmacology, 8th Edition, 2019, 860-872.
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
