This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

Acebrophylline contains an active component as Acebrophylline. It is a medication used to manage respiratory conditions such as bronchial asthma and chronic obstructive pulmonary disease (COPD). It can alleviate symptoms associated with respiratory conditions, such as wheezing, coughing, shortness of breath, and chest tightness. Improving bronchodilation and reducing airway inflammation can help individuals experience fewer and less severe symptoms. This medication has improved lung function parameters such as forced expiratory volume in one second (FEV1) and peak expiratory flow rate (PEFR). These improvements indicate better respiratory function and can contribute to overall lung health.

Mechanism of Action of undefined

Acebrophylline contains theophylline and ambroxol. Theophylline is a bronchodilator that helps relax the muscles in the airways, allowing easier breathing. It also has anti-inflammatory effects on the respiratory system. On the other hand, Ambroxol is a mucolytic agent that helps break down and thin the mucus in the airways, making it easier to cough up. By combining these two components, this medication aims to provide both bronchodilation and mucus clearance, thus improving symptoms associated with respiratory conditions.

Uses of undefined

Acebrophylline is used to manage respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD).

undefined Drug administaration and Dosage available

To use Acebrophylline, follow the instructions provided by your healthcare provider or as indicated on the medication label. Swallow them whole with a full glass of water, with or without food, as directed. The dosage and duration of treatment will depend on the type and severity of the infection.

Warnings, Precautions and Side Effects of undefined

Warnings

Acebrophylline carries important warnings that should be considered when using the medication. Hypersensitivity reactions, including skin rash and difficulty breathing. This medication can cause cardiac effects such as increased heart rate, palpitations, and arrhythmias are possible, and caution is advised in individuals with cardiac conditions. This medication may lower the seizure threshold, necessitating close monitoring in patients with a history of seizures. The medication may exacerbate gastrointestinal disorders. It should not be used for acute asthma or COPD exacerbations. Abrupt discontinuation can lead to withdrawal symptoms.

Precautions

When using Acebrophylline, it is important to be aware of potential warnings. It is important to be aware of these potential skin reactions, seek medical help if any skin changes occur, monitor for these symptoms, and contact a healthcare provider if they arise. Caution is recommended in individuals with peptic ulcers or GERD. Vigilance and prompt reporting of new or worsening symptoms are essential to ensure Acebrophylline's safe and effective use. Contact your healthcare provider if you experience cardiac disease or seizures. Regular monitoring of respiratory function is essential to assess treatment effectiveness. Avoid alcohol consumption while taking Acebrophylline, as it can interact with the medication and potentially increase the risk of side effects. Adhering to these precautions and following your healthcare provider's guidance can help ensure Acebrophylline's safe and effective use.

Side Effects

Common side effects of acebrophylline may include gastrointestinal disturbances such as nausea, vomiting, and abdominal discomfort. Other commonly reported side effects include headache, dizziness, heartburn, and changes in taste sensation. Less frequently, individuals may experience insomnia, tremors, palpitations, and allergic reactions such as rash or itching.

Word Of Advice

Inform your healthcare provider about any known allergies or sensitivities to Acebrophylline and any other medications or substances you are currently taking. Additionally, disclose your medical history, especially if you have a history of kidney disease, liver disease, gastrointestinal disorders, or blood clotting disorders. Caution should be exercised in individuals with cardiac conditions, seizures, gastrointestinal disorders, hepatic or renal impairment, and dose adjustments or alternative treatments may be required. Pregnant and breastfeeding women should consult a doctor before taking it. It is crucial to complete the full course of treatment as prescribed and not to skip any doses, even if symptoms improve, to ensure the infection is fully treated. Geriatric and pediatric populations may require dosage adjustments. Consulting with a healthcare professional is crucial to ensure the safe and appropriate use of acebrophylline.

Frequently Asked Question

References

  1. KD Tripathi, Essentials of Medical Pharmacology, Drugs for cough and bronchial asthma, 7th edition, 2013, 219
  2. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Pulmonary pharmacology, 12th edition, 2011, 1040-1044
  3. La Renon Healthcare Private Limited, [ Accessed on 17th June 2023], https://www.larenon.com/wp-content/uploads/2020/06/1.-Aphyren-N-LBL_ctc.pdf

Disclaimer

The drug information on this page is different from medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.