This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Background and Date of Approval
Desidustat is an erythropoiesis-stimulating agent which belongs to the medication class known as hypoxia-inducible factor-prolyl hydroxylase (HIF-PH) inhibitor.
Mechanism of Action of undefined
Desidustat belongs to the group HIF-PH inhibitors that activate hypoxia-inducible factors (HIF), stimulate the production of red blood cells, and improve the body's utilization of iron.
Uses of undefined
Desidustat is used to treat anemia in patients with chronic kidney disease by stimulating the production of red blood cells.
undefined Drug administaration and Dosage available
Take the Desidustat as your physician advises. Take medicine at a fixed time. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the tablet if your doctor advises you to stop.
Warnings, Precautions and Side Effects of undefined
Warnings
Do not consume Desidustat if you are allergic to Desidustat or any of its ingredients in the medication. Before starting the treatment, inform your doctor if you have a history of seizures, strokes, or blood disorders (sickle cell anemia). Always check the expiry date before consuming the medicine.
Precautions
Notify your doctor if you are pregnant, planning to get pregnant, or think you may be pregnant or breastfeeding. Before taking Desidustat, inform your doctor if you are pregnant, planning to get pregnant, or think you may be pregnant or are breastfeeding. Your iron levels and blood pressure will be regularly monitored before and during the treatment. It is unknown whether Desidustat alters driving ability. However, if you experience side effects like tiredness or drowsiness, avoid driving and using machines.
Side Effects
The most common side effects of Desidustat are vomiting, abdominal pain, fever, headache, weakness, and peripheral edema (accumulation of fluid).
Word Of Advice
Before starting the treatment, inform your doctor about all the underlying medical conditions. Do not stop the medicine until your doctor advises. Do not double-dose the medicine to make up for a forgotten dose. Notify your doctor if you experience any serious side effects. Contact your doctor for more information.
Frequently Asked Question
References
- Clinicaltrials.gov, NCT04012957, [Revised on 24th Nov 2021] [Accessed on 27th June 2023], https://clinicaltrials.gov/ct2/show/NCT04012957
- J. Goddard, A.N. Turner, Kidney and Urinary Tract Disease, Davidson’s Principles and Practice of Medicine, 22nd Edition, 2014, 461-523.
- Amit A Joharapurkar et al., Prolyl Hydroxylase Inhibitors: A Breakthrough in the Therapy of Anemia Associated with Chronic Diseases, J. Med. Chem. 2018, 61, 16, 6964–6982, https://pubs.acs.org/doi/abs/10.1021/acs.jmedchem.7b01686
Disclaimer
The drug information on this page is not a substitute for medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you are eligible to receive this treatment.
