Uses of undefined

Zoledronic Acid Injection has been developed to treat osteoporosis and prevent bone complications in patients diagnosed with bone cancer. A condition called tumor-induced hypercalcemia is common among people diagnosed with cancer. Zoledronic acid Injection is indicated to reduce blood calcium levels in such conditions.

undefined Drug administaration and Dosage available

Zoledronic Acid Injection is available as a single-dose vial for injection in doses 4mg and 5mg. It is intended for administration as an intravenous infusion after reconstitution. Your healthcare provider will prescribe an accurate dose depending on your health condition. If you have been diagnosed with a kidney problem, your doctor will administer a lower dose.

Warnings, Precautions and Side Effects of undefined

Warnings

During the Zoledronic Acid Injection treatment, your doctor may periodically monitor your blood calcium, phosphorus, and magnesium and kidney parameters to prevent serious complications. Get a dental appointment before starting treatment with Zoledronic Acid Injection. Tell your healthcare provider before starting treatment with Zoledronic Acid Injection if you have been diagnosed with hypocalcemia, a problem in your heart or kidneys, or you are undergoing chemotherapy/radiotherapy. Get immediate medical attention if you have breathlessness or allergies. 

Precautions

Zoledronic Acid Injection is not recommended for use during pregnancy and breastfeeding. Tell your healthcare provider before starting this treatment if you are pregnant, think you might be pregnant, breastfeeding, or planning to have a baby.

Side Effects

The common side effects that are likely to occur while you are on the treatment with Zoledronic Acid Injection are low levels of calcium and phosphorus, headache, flu, tiredness, weakness, drowsiness, chills, pain in the bone, joint and muscle, nausea, vomiting, conjunctivitis and anemia. If you experience any reactions like rashes, bruising, swelling, and itching at the Injection site, report to your doctor immediately.

Word Of Advice

Zoledronic Acid Injection rarely causes dizziness and sickness. However, it is advisable to avoid driving or handling machines during this treatment if you feel uncomfortable. Drink sufficient water before treatment to prevent dehydration.

Frequently Asked Question

• Who should not use Zoledronic Acid Injection?
• Zoledronic Acid Injection is not recommended for children/adolescents below the age of 18 years, breastfeeding women and patients who are hypersensitive to Zoledronic Acid, bisphosphonates or its excipients.

• How do you know if you are having hypocalcemia?
• Muscle cramps, dry skin, burning sensation, irregular heartbeat, seizures and spasm are some of the symptoms that indicate hypocalcaemia.

• How to manage side effects of Zoledronic acid?
• Pay close attention to your symptoms during treatment with Zoledronic acid and report to your healthcare provider if you experience any unusual symptoms. Maintain proper oral and dental hygiene during this treatment.

• How is Zoledronic Acid Injection administered?
• Zoledronic Acid Injection is given intravenously as an infusion. The recommended dosing to prevent complications due to bone cancer is one infusion every three to four weeks. To reduce the amount of calcium in your blood, you will be administered only one infusion of Zoledronic acid.

• When should you contact your doctor?
• Reach out to your healthcare provider immediately if you experience symptoms like loose teeth, pain, swelling, sores or discharge from mouth or teeth as these symptoms indicate the possibility of a condition called osteonecrosis of the jaw.

• What should you do if you overdose on Zoledronic Acid?
• Report to your physician immediately if you overdose on Zoledronic Acid. Your physician will monitor blood calcium, magnesium and phosphorus, and kidney panel and would suggest discontinuation of Zoledronic Acid Injection if necessary. If your calcium levels go too low, you will be administered with calcium infusion.

• What should you not take with Zoledronic Acid Injection?
• Do not take Zoledronic Acid Injection if you are taking aminoglycoside antibiotics, calcitonin, thalidomide or other anti-angiogenic medications. Also, tell your physician if you are taking any other prescription medication, over the counter drugs, vitamin or herbal supplements.